Showing posts with label Doxycycline. Show all posts
Showing posts with label Doxycycline. Show all posts

18 August 2011

Marvelous Results

Though Lyme treatment may be a marathon instead of the sprint we would like it to be, sometimes good results come more quickly than anticipated.

Yesterday I received Thane's lab results. I was overjoyed! His liver enzymes that had been horribly elevated are now back in the normal range- in fact low normal to mid normal. Some of his enzymes are even lower than pre-Doxy including one of the elevated ones. Its a very good feeling amidst the upheaval of Lyme disease that has dramatically changed our life and eliminated our summer adventures.

I know that I can not get complacent because of the good that has taken place though. The mere fact that a drug reaction could bring with it such an assault. He will continue to receive the Milk Thistle just as before to prevent any setbacks in the road through Lyme. Honestly I now look at that reaction to Doxycycline that he had, as devastating and hard to deal with as it was, as a good thing. If it had not been for that reaction, I would not have learned about his liver difficulties going on so quickly and the turn around might have taken a much longer path to resolve.

Today I am happy though for good reason.

Thane had a good day today so we did an errand in town. It was nice to get some walking in with him as well as to realize that sometimes his goofing off is more about boredom of the route than anything else. I let him choose a route to come home and he excelled so well. My back wasn't thrilled at the horrible sidewalk surface. It seems there will have to be a law before people take their sidewalk upkeep responsibilities seriously. In some places in our town, it'd be easier if it was just a dirt or gravel path than the sidewalks that are there. Up town where I live takes it more seriously for some reason, but not so much the case down town. Thane was enjoying himself and working exceptionally so I put up with it for a while. Now my back is yelling about that decision- but hey, sometimes a girls gotta give her guide some variety!

09 August 2011

Living and Working with Fluctuations of Lyme Disease and its Treatment

It has been a while since I did an update, so thought I would take a down day to do just that. Thane and I have had some good days this week. He has a real gusto about his job again- about wanting to Go, Go, Go smile Though there are some really great things taking place- more calmness in harness pull, ability to take in some distance, better focus with each passing day, and great attention to what I am needing at the moment- there are also the tough aspects of living with and working through Lyme. The aspects especially of how the disease has its good and bad times, much like living with MCS does.

There are the appetite issues, the constant reminder of the disease as you dose supplements and meds, the moments when you realize you were right all along about Denosyl causing problems, the bad decisions in terms of work that left your guide overdone and needing to take steps back.

I have to remind myself every once in a while that though I have baptized myself in knowledge about this disease; about how it works- I also have to give myself a break when I make a bad decision. In other words, I need to forgive myself for when I chose a course of action that was not the right one.

Today is a down day after two shopping days. The freezer and cupboards are full enough that anything we need can wait until we both bounce back.

I had tried Denosyl a second time. I did so because I could not be positive that either Tripett or the higher probiotics dose played some role in the GI symptoms. I also could not be positive that the chewing the first time was not done out of boredom or stress or even aspects of the Lyme spirochets. The change in his appetite, I was seriously attributing to the disease itself. The sudden increase in sound reactivity, I was uncertain of the cause initially when I first tried Denosyl as the disease could be at play there.

After some tweaking of supplements for a few days I tried again. After three doses it was pretty clear I had been right to blame the Denosyl.

-Thane's appetite had tapered off a lot, but usually I did manage to get him to consume most his food by days' end.
-Yesterday Thane was back to multiple bowel movements[ one where he was working in harness and before I knew it he was pooping. For those reading this who may not know, a guide is trained to go on command rather than to just choosing to go when they want. At least he pulled into some dirt before going smile
-His heightened sound reactivity made it picture clear that there was a big problem with Denosyl when my smoke detector decided it was time to warn of low battery. Oh so perfect timing NOT! I change them every year before my section 8 inspection, but those did not last a year! While we were out shopping, better batteries designed specifically for smoke detectors were installed, thanks to my Dad. There were other issues with sensitivity while we were out, but overall he worked pretty good as long as we took our time at things.
-Lastly I had noticed that Thane was squatting to pee more often. When he did not raise his leg on his potty station, a place he always raises his leg, I knew something was up. He laid under the desk either chewing at his knee or resting- not wanting to play much and when he did play he did not run for the ball, but walked. It was clear he was hurting- whether from the use of Denosyl, from the disease, or from over-doing I can't be sure, but since he is dramatically improved 24 hrs after pulling the Denosyl, I suspect it was at least partially responsible in this area as well.

The moral to all of this is despite what Nutramax says about Denosyl only having one rare side effect of vomiting, there can be many other side effects dependent on the dog. The only place one finds information on this is through the manufacturer. There are no alternative resources and they were the only ones involved in its testing and marketing. This is not to say that it's a bad supplement. After all for most dogs there may really be no side effects. If you have a sensitive dog though where synthetic drugs and supplements are an issue, there's reason to be cautious with this supplement and start with a lower dose and work up rather than starting with the recommended dosage.

I asked for Denosyl because I wanted to offer Thane the very best in liver healing after the damage that Doxycycline had done to his liver. I just wanted to help him the best I knew to. For now, I will continue with the two doses a day of his Milk Thistle Complex that includes  other liver friendly herbs and ingredients.

If I allow it to, this could be beyond overwhelming for me to have to constantly question whether Thane is up for working in any given situation. A high drive dog is going to act high drive often times when they are not up to the task. It will take great skill in evaluating what we can and can not do- a big learning curve for sure.

Denosyl a third time.

Hopefully when we wake up tomorrow, it will be a good day for both of us- a chance to get out again. If its not the case, we will roll with the punches.

02 August 2011

Sometimes it's Baby Steps

Thane and I are taking each day as it comes. There are days when it really is hard for me to swallow the path we are on- and others where I take it no different than I take my own chronic health needs- that is, one day at a time. Some days are the top floor while others tanked out or somewhere in between. I'm learning to really listen to Thane- to what he wants, needs, and even to when he feels alright but would just rather veg much like days I get myself from time to time.

Today was a vegging day. It was beautiful out again. It hit 81 in Portland today- probably a few degrees warmer here. I'm learning to let my frustration of not being able to have our adventures roll off me in much the way we would let a bad decision roll off. I'm taking advantage of the down times to catch up on regular laundry, working gear laundry that we have limited quantities of, sewing tasks like new braces, and even some work on my housing re-cert paperwork. All of this happens amidst *other play* (stuffies), *throwee* (balls thrown from the ball launcher), encouraging Thane to perform his indoor tasks, and just plain and simply enjoyment of the down time rather than always focusing on why it is that we are not out discovering some new niche in the world that is fun to explore.

Tomorrow is a toss up. A lot will depend upon what both of us are feeling like. Its a day that I hope can be spent with Thane at my side on an errand, but at the same time I am not fooling myself into believing that he will be the same dog at my side who was there that fateful day when he probably saved our lives a couple months ago. All in due time, I tell myself.

The more I learn about Lyme, the more I wish it was taken more seriously by vets everywhere. I wish at the very least, that vets brought the topic up with their clients (and yes in non-endemic areas too). Maybe through Thane's journey, I can educate others in my area enough that they will take pause to become aware of the symptoms that can point to a Lyme's diagnosis as opposed to just stress or allergies.

Maybe this is my new call. Perhaps I was meant to have a cause for each successor I have. I certainly hope that does not become reality however- believe me two causes are plenty in a lifetime (three if you count educating people about MCS).

I find myself putting our days on a point scale- you know that typical scale of one to ten. For our purposes, I'm going to call one the worst and ten the best. Today I consider a six despite Thane wanting to stay home. My criterion are much lower however than they were upon diagnosis due to how bad things actually got while Thane was on Doxy.

Today he chewed just slight itches for a moment, he did not have loose poop, and by days end he had ate all his food I planned for this day. He played and even got down right silly clown with his frib in the evening time. He took a nap while I sewed my new brace, entertained himself while I did a bit of scanning and only seemed to nap a normal amount as opposed to the excess one gets used to seeing with Lymes.

Tomorrow is its own new day. I may get up and discover that everything has been blown to smithereens with regards to my plans and how Thane is doing. If that is the case, I will adapt/ adjust to whatever changes I must make- because after all what is most important right now is not the assistance he can provide me on my errands, but whether or not he is capable of assisting me or not.

This is not the 100M dash at the Olympics, it is in the class of the pentathalon, marathon, Tour de France. There will be a time for celebrating one day, but today it is all about those baby steps of accomplishment. I see progress today and frankly that really is all that counts.

31 July 2011

Resenting Lyme

Lyme is a roller coaster ride. If anyone tells you differently they are fooling themselves and you. It is a roller coaster ride of waxing and waning- not just in symptoms but in emotions as well. These yoyoing emotions also are not just for the one suffering from the disease, but for their caregivers too.

Though I know people who have had Lyme or who presently do, I was never right there in their daily life and struggles to experience any of this first hand. It's all especially hard if the individual with the disease also happens to be one that you rely upon- like a service animal.

I'm no stranger to chronic health difficulties- not for myself and not for my service dogs. That said, I have grown accustom to being able to rely upon Thane as a *healthier* service dog- to help me at home from retrieves, to door tugs, and  to nudging doors open or closed, to turning out the light, to helping me undress. I have become even more accustom to him in public though- his guide work impeccable, his boredom games something that has made me grow as a trainer and handler- but above all I never felt so resentful about anything, not even in Met's life. Don't get me wrong I  DO NOT resent Thane, it's the Lyme Borreliosis spirochetes that has my focus of resentment for all its taken from us.

I love Thane with all my heart. It hurts though deep in my soul that I can not snap my fingers and return him to health. Though Thane is doing better and needs his exercise and even outings, he is not the dependable perfection in guiding and decision-making I had come to expect. Now the mini guide has become a *must have* tool for not just street crossings where it has been invaluable, but to the entire trek we make from the time we leave our walkway to the time we enter our apartment on the return. This is sad to me. I feel almost lost in a maze by what the disease has done; has taken from us.

There are things that just impact our work. I want to have the memories in real life again and yet I have to wonder when, if ever, that will happen again.

When Thane is given drugs, Thane is different. I never noticed it when he was given antibiotics before so I did not expect it now. That said, his antibiotics are not the only new thing he is taking- he has been on milk thistle twice a day and had Denosyl added a couple of days ago.

Border Collies or at least my Border Collies have needed to keep to routine. If Met missed more than two or three days of walks or outings, it was as though I was working a green dog until he got settled into routine again. Thane has not been quite as bad as that, but still a week seems to be his top before I feel like I have a green dog at my side again. When you add drugs to the mix and up the ante from a week to nearly a month with a dog recovering from the implications of a severe drug reaction and a history of  weak blood brain barrier symptoms- my gosh!

Thane has always had a specific type of response to chemical drugs like Capstar. It's bizarre, but he is less clear headed and has this absolute necessity to follow the sidewalk or floor path edge. Its not just walking on the edge of the sidewalk or along a wall, but an actual weaving aong the sidewalk edge, trees, obstacles etc. I feel like I am doing weave poles when these reactions hit. When he needs Capstar, it's short lived and followed by two or three doses of milk thistle since weak blood brain barrier symptoms can merely be due to a slower drug clearance. The key here is that it is short lived because it is not needed every single day.

Right now I have no idea what the trigger really is for his reaction which appears magnified at least four times that of how he responds on Capstar. It could be the amoxicillin, it could be the milk thistle, it could be the Denosyl, or it could be non-med or supplement based and be tripett or liver clearance for everything due to his liver involvement that followed the use of Doxycycline, or an unrelated issue altogether that just becomes apparent when drugs or less tolerated supplements are in use, or a symptom of the disease itself  (hard to accept that latter possibility though).

It's understandable that I should be frustrated right now, but resentful- I can't get my head around this. That tick did not know it was sick It did not necessarily do this to us on purpose other than taking a blood meal is how it survives, but it happened nonetheless and I am left to work through what emotions I have from one day to the next.

Yesterday I was full of optimism, today I just want whoever left me with a faulty replica of Thane, to return the original- it's not funny any more!

27 July 2011

The Meaning Behind, Guiding Through Lyme

I meant to write this first and forgot. I wanted to share why I chose the name I did for this blog- what it means to me.

Guiding Through Lyme has a dual meaning to me. One of course will be the path that Thane's particular course with Lyme takes us in. We've already seen that his course is not going to be a typical one after he reacted to Doxycycline. This is a disease though that will have ups and downs and Thane himself will guide what path we must take.

The second meaning of the blog has to do with our working partnership. It has to do with working as a team while living with chronic Lyme Disease. I've got experience working with a service dog who had chronic health needs already so that won't be new to me. This disease is different and as such I know it is going to govern just how much and what Thane can do for a while, but it will be good for me (and you) for this blog to not be just about the bad days, but that you see the days when Lyme does not feel like it owns us.

I know how bleak it can be, but I also know of those who have triumphed and won so its important to share the wins along the way too. Don't you think? smile

26 July 2011

Answers

There are times when we get answers that resolutions can be swift as a result. When I set my mind on testing Thane for Lyme disease, I thought I was doing it as a *preventative* measure for not leaving stones unturned that could cause problems in the health and longevity of a team, but I certainly was not of the belief that he had it.

At that point, I was being a good owner and handler providing my dog with the very best in prevention and health maintenance. It was not until later that I would remember the strange dark bump on Thane's abdomen that was later replaced with the hive like reaction common in most after a tick has detached.

I pursued testing because of the proactive stand my friend Sharon at the After Gadget blog has held. Through her fight with Lyme and other co-infections as well as Gadget's experience with Lyme, she has done an awesome job in showing us that Lyme is not just a North East/ East coast  thing, but that it can be wherever you live.

It was hard for me to digest when my vet said that Thane's newer symptoms were leading her to believe that TBD (tick borne disease) might actually be his problem, but she continued by saying that our ticks are not generally diseased.

Thane blew that out of the water when his tests came back with a diagnosis of Lyme disease. By the time the drugs were here (needed a compounder) Thane had begun to enter a collapse. I was unaware how bad off he was and as a result we barely made it back home. It was heart-breaking and scarey, but having a friend who knew what I was going through truly made all the difference in how I handled the next week with Thane.

One of the hardest things was to put Thane in his crate and head out with my guide cane and mini-guide to do my shopping errands alone. To say I got a real lesson in just how much Thane does would be a huge understatement. It was not easy, but someone had to get food in our house if we wanted to eat. grin

It's been hard for me to deal with other things too though- summers are when Thane and I head off for adventuring. Its a time of just really trying new things that make me trust in him completely. Its a time when our bond and teamwork are magnified because of the experiences we have together in parts unknown. This year however, between the ridiculous nature of the weather and Thane's health, the furthest we have gone is New Seasons and in doing that trip, we barely made it home.

Summers are my lifeline to surviving the nine to ten months of rain and mud and trials of trying to ride public transit amidst that kind of weather. I rely on the pick-me-up I get from our sun filled days of adventure to carry me through until the next summer surfaces. Now, this year, I'm supplementing with Vitamin D because as much sun as I get when taking Thane busy or for walks when he is able just aint going to cut my needs.

Despite all of this, I felt like I was doing OK. That is until Thane crashed again. Though its turned out alright now, the experience of him reacting to Doxycycline (and me suspecting the drug, but being told to continue its use) will haunt me for a while. Thankfully we saw a specialist the very next day who suspected the same, pulled the drug, and placed him on Amoxicillin instead. I am cautiously optimistic with the path of the past week on this drug.

During the crash Thane experienced, I received some hurtful emails amidst some really supportive ones. You know who you are- the people who carried me through. I can't thank you enough for helping me take a step back from those whose views were essentially that of blame instead of support. You carried me through some of the most tumultuous days I have experienced since the passing of Met. For that I am most grateful.

I know there will be ups and downs along the road back for Thane and I. I also know that Thane is not going to get better in a week or a month- afterall the spirochets have had two years to wreak havoc without being stopped. I am trying not to live with regrets. I can't go back and change that fateful day in June 2009 when I felt a weird bump on Thane and told myself to keep an eye on it. I'd personally never seen what an attached tick looked like on a body part even when I was sighted (though the vet found one on Met when I had him only two weeks, he removed it without me seeing it on him) so blaming myself for this isn't going to help me and it certainly won't help Thane.

On the positive side, I kept looking for answers to his ever changing symptoms from skin and coat, to symptoms that appeared hormonal, to musculoskeletal, to neurological. I am glad that I stuck with it and did not come to a place where I just blew it off because nothing ever panned out. Some people think my search for answers to be a desire to find something wrong. That could not be the furthest thing from the truth. By sticking with it, I found that Thane had his own journey to walk- a journey to teach me and others that Lyme is in fact here in the Pacific NorthWest.